HBV Target gene Detail Information

> TMEM216 Gene Search Result

Gene Information

Gene Name	TMEM216
Gene ID	51259
Gene Full Name	transmembrane protein 216
Gene Alias	HSPC244
Transcripts	ENSG00000187049
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q9P0N5
HGNC ID	HGNC:25018
VEGA ID	OTTHUMG00000168146
OMIM ID	613277
String ID	9606.ENSP00000440638
PharmGKB ID	PA162406553

Target gene [TMEM216] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1400113	chr11	262	384	249	895	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEM216 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM216 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).