HBV Target gene Detail Information

> TMEM192 Gene Search Result

Gene Information

Gene Name	TMEM192
Gene ID	201931
Gene Full Name	transmembrane protein 192
Transcripts	ENSG00000170088
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endosomes;Lysosomes;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	Q8IY95
HGNC ID	HGNC:26775
VEGA ID	OTTHUMG00000161254
String ID	9606.ENSP00000305069
PharmGKB ID	PA162406273

Target gene [TMEM192] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006675	chr4	34	1		35	View
1006676	chr4	26	6	3	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEM192 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM192 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).