HBV Target gene Detail Information

> TMEM181 Gene Search Result

Gene Information

Gene Name	TMEM181
Gene ID	57583
Gene Full Name	transmembrane protein 181
Gene Alias	GPR178; KIAA1423
Transcripts	ENSG00000146433
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Golgi apparatus;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9P2C4
HGNC ID	HGNC:20958
VEGA ID	OTTHUMG00000015913
OMIM ID	613209
String ID	9606.ENSP00000356057
PharmGKB ID	PA162406036

Target gene [TMEM181] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009521	chr6	10	5		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEM181 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM181 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).