HIV Target gene Detail Information

> TMEM18 Gene Search Result

Gene Information

Gene Name	TMEM18
Gene ID	129787
Gene Full Name	transmembrane protein 18
Gene Alias	lncND
Transcripts	ENSG00000151353
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	Q96B42
HGNC ID	HGNC:25257
VEGA ID	OTTHUMG00000151381
OMIM ID	613220
String ID	9606.ENSP00000281017
PharmGKB ID	PA134873089

Target gene [TMEM18] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000868	chr2	99	62	100	261	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMEM18 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM18 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMEM18 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM18 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).