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HTLV1 Target gene Detail Information

> TMEM179 Gene Search Result


Gene Information
Gene Name TMEM179
Gene ID 388021
Gene Full Name transmembrane protein 179
Gene Alias C14orf90; TMEM179A
Transcripts ENSG00000276342
Virus HTLV1
Gene Type protein coding
HPA Location Info Mitochondria;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q6ZVK1
HGNC ID HGNC:20137
VEGA ID OTTHUMG00000190144
String ID 9606.ENSP00000450958
PharmGKB ID PA162405995
Target gene [TMEM179] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6006143 chr14 49 25 74 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TMEM179 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMEM179 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of TMEM179 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMEM179 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).