HIV Target gene Detail Information

> TMEM177 Gene Search Result

Gene Information

Gene Name	TMEM177
Gene ID	80775
Gene Full Name	transmembrane protein 177
Transcripts	ENSG00000144120
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q53S58
HGNC ID	HGNC:28143
VEGA ID	OTTHUMG00000153312
String ID	9606.ENSP00000402661
PharmGKB ID	PA162405985

Target gene [TMEM177] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010922	chr2	5	3		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMEM177 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM177 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).