HTLV1 Target gene Detail Information

> TMEM170A Gene Search Result

Gene Information

Gene Name	TMEM170A
Gene ID	124491
Gene Full Name	transmembrane protein 170A
Gene Alias	TMEM170
Transcripts	ENSG00000166822
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	Q8WVE7
HGNC ID	HGNC:29577
VEGA ID	OTTHUMG00000137614
String ID	9606.ENSP00000454404
PharmGKB ID	PA162405922

Target gene [TMEM170A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000525	chr16	1292	16	8	1316	View
6010274	chr16	30	2		32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TMEM170A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMEM170A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).