HBV Target gene Detail Information

> TMEM154 Gene Search Result

Gene Information

Gene Name	TMEM154
Gene ID	201799
Gene Full Name	transmembrane protein 154
Transcripts	ENSG00000170006
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q6P9G4
HGNC ID	HGNC:26489
VEGA ID	OTTHUMG00000161463
String ID	9606.ENSP00000302144
PharmGKB ID	PA145007430

Target gene [TMEM154] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006149	chr4	4	31	7	42	View
1006578	chr4	4	27	5	36	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEM154 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM154 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).