HIV Target gene Detail Information

> TMEM131 Gene Search Result

Gene Information

Gene Name	TMEM131
Gene ID	23505
Gene Full Name	transmembrane protein 131
Gene Alias	RW1; CC28; YR-23; PRO1048
Transcripts	ENSG00000075568
Virus	HIV
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q92545
HGNC ID	HGNC:30366
VEGA ID	OTTHUMG00000153061
OMIM ID	615659
String ID	9606.ENSP00000186436
PharmGKB ID	PA143485651

Target gene [TMEM131] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002536	chr2	65	24	1	90	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMEM131 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM131 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMEM131 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM131 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).