HIV Target gene Detail Information

> TMEM115 Gene Search Result

Gene Information

Gene Name	TMEM115
Gene ID	11070
Gene Full Name	transmembrane protein 115
Gene Alias	PL6
Transcripts	ENSG00000126062
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins
Uniport_ID	Q12893
HGNC ID	HGNC:30055
VEGA ID	OTTHUMG00000044212
OMIM ID	607069
String ID	9606.ENSP00000266025
PharmGKB ID	PA143485636

Target gene [TMEM115] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000538	chr3	381	4		385	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMEM115 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM115 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMEM115 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM115 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).