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HBV Target gene Detail Information

> TMEM107 Gene Search Result


Gene Information
Gene Name TMEM107
Gene ID 84314
Gene Full Name transmembrane protein 107
Gene Alias MKS13; JBTS29; GRVS638; PRO1268
Transcripts ENSG00000179029
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;Midbody ring;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q6UX40
HGNC ID HGNC:28128
VEGA ID OTTHUMG00000166276
OMIM ID 616183
String ID 9606.ENSP00000314116
PharmGKB ID PA142670758
Target gene [TMEM107] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000093 chr17 2185 3695 1385 7265 View
1000098 chr17 2262 3384 1314 6960 View
1000109 chr17 839 4273 1458 6570 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TMEM107 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TMEM107 expression: Low -> High
Lollipop of TMEM107 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TMEM107 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TMEM107 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM107 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).