HBV Target gene Detail Information

> TMEFF2 Gene Search Result

Gene Information

Gene Name	TMEFF2
Gene ID	23671
Gene Full Name	transmembrane protein with EGF like and two follistatin like domains 2
Gene Alias	TR; HPP1; TPEF; TR-2; TENB2; CT120.2
Transcripts	ENSG00000144339
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Predicted secreted proteins
Gene Function	Suppressor gene
Uniport_ID	Q9UIK5
HGNC ID	HGNC:11867
VEGA ID	OTTHUMG00000132723
OMIM ID	605734
String ID	9606.ENSP00000272771
PharmGKB ID	PA36568

Target gene [TMEFF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013148	chr2	1	4		5	View
1016100	chr2	1	1		2	View
1401225	chr2	1	4		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEFF2 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEFF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).