HBV Target gene Detail Information

> TMEFF1 Gene Search Result

Gene Information

Gene Name	TMEFF1
Gene ID	8577
Gene Full Name	transmembrane protein with EGF like and two follistatin like domains 1
Gene Alias	TR-1; H7365; C9orf2; CT120.1
Transcripts	ENSG00000241697
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	Q8IYR6
HGNC ID	HGNC:11866
VEGA ID	OTTHUMG00000020367
OMIM ID	603421
String ID	9606.ENSP00000364013
PharmGKB ID	PA36567

Target gene [TMEFF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007651	chr9	5	13	7	25	View
1405010	chr9	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEFF1 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEFF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).