HIV Target gene Detail Information

> TMED2 Gene Search Result

Gene Information

Gene Name	TMED2
Gene ID	10959
Gene Full Name	transmembrane p24 trafficking protein 2
Gene Alias	p24; P24A; RNP24; p24b1; p24beta1
Transcripts	ENSG00000086598
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q15363
HGNC ID	HGNC:16996
VEGA ID	OTTHUMG00000168694
String ID	9606.ENSP00000262225
PharmGKB ID	PA142670796

Target gene [TMED2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000394	chr12	44	371	78	493	View
4000402	chr12	42	371	78	491	View
4000403	chr12	42	371	78	491	View
4000440	chr12	22	363	77	462	View
4000441	chr12	22	363	77	462	View
4000445	chr12	20	363	77	460	View
4010485	chr12	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMED2 expression and immune infiltrating cell level correlation result in HIV+ samples
TMED2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMED2 expression and immune infiltrating cell level correlation result in HIV+ samples
TMED2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).