HIV Target gene Detail Information

> TMED10 Gene Search Result

Gene Information

Gene Name	TMED10
Gene ID	10972
Gene Full Name	transmembrane p24 trafficking protein 10
Gene Alias	p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)
Transcripts	ENSG00000170348
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	P49755
HGNC ID	HGNC:16998
VEGA ID	OTTHUMG00000171771
OMIM ID	605406
String ID	9606.ENSP00000303145
PharmGKB ID	PA128394579

Target gene [TMED10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000528	chr14	389	7		396	View
4000624	chr14	54	162	125	341	View
4000936	chr14	217	13	15	245	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMED10 expression and immune infiltrating cell level correlation result in HIV+ samples
TMED10 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMED10 expression and immune infiltrating cell level correlation result in HIV+ samples
TMED10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).