HIV Target gene Detail Information

> TMBIM4 Gene Search Result

Gene Information

Gene Name	TMBIM4
Gene ID	51643
Gene Full Name	transmembrane BAX inhibitor motif containing 4
Gene Alias	S1R; GAAP; LFG4; ZPRO; CGI-119
Transcripts	ENSG00000155957
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9HC24
HGNC ID	HGNC:24257
VEGA ID	OTTHUMG00000168973
OMIM ID	616874
String ID	9606.ENSP00000286424
PharmGKB ID	PA142670805

Target gene [TMBIM4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002677	chr12	33	25	26	84	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMBIM4 expression and immune infiltrating cell level correlation result in HIV+ samples
TMBIM4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMBIM4 expression and immune infiltrating cell level correlation result in HIV+ samples
TMBIM4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).