HIV Target gene Detail Information

> TLN2 Gene Search Result

Gene Information

Gene Name	TLN2
Gene ID	83660
Gene Full Name	talin 2
Gene Alias	ILWEQ
Transcripts	ENSG00000171914
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Focal adhesion sites;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y4G6
HGNC ID	HGNC:15447
VEGA ID	OTTHUMG00000133679
OMIM ID	607349
String ID	9606.ENSP00000453508
PharmGKB ID	PA37958

Target gene [TLN2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010287	chr15	8	1		9	View
4012896	chr15	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TLN2 expression and immune infiltrating cell level correlation result in HIV+ samples
TLN2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).