HBV Target gene Detail Information

> TLE4 Gene Search Result

Gene Information

Gene Name	TLE4
Gene ID	7091
Gene Full Name	transducin like enhancer of split 4
Gene Alias	ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI)
Transcripts	ENSG00000106829
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q04727
HGNC ID	HGNC:11840
VEGA ID	OTTHUMG00000020072
OMIM ID	605132
String ID	9606.ENSP00000365720
PharmGKB ID	PA36542

Target gene [TLE4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004516	chr9	19	36	25	80	View
1013637	chr9	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TLE4 expression and immune infiltrating cell level correlation result in HBV+ samples
TLE4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).