HBV Target gene Detail Information

> TLE2 Gene Search Result

Gene Information

Gene Name	TLE2
Gene ID	7089
Gene Full Name	transducin like enhancer of split 2
Gene Alias	ESG; ESG2; GRG2
Transcripts	ENSG00000065717
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Focal adhesion sites;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q04725
HGNC ID	HGNC:11838
VEGA ID	OTTHUMG00000180613
OMIM ID	601041
String ID	9606.ENSP00000466542
PharmGKB ID	PA36540

Target gene [TLE2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002385	chr19	196	17	69	282	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TLE2 expression and immune infiltrating cell level correlation result in HBV+ samples
TLE2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).