HTLV1 Target gene Detail Information

> TIGIT Gene Search Result

Gene Information

Gene Name	TIGIT
Gene ID	201633
Gene Full Name	T cell immunoreceptor with Ig and ITIM domains
Gene Alias	VSIG9; VSTM3; WUCAM
Transcripts	ENSG00000181847
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q495A1
HGNC ID	HGNC:26838
VEGA ID	OTTHUMG00000159331
OMIM ID	612859
String ID	9606.ENSP00000419085
PharmGKB ID	PA164726482

Target gene [TIGIT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000988	chr3	285	313	58	656	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TIGIT expression and immune infiltrating cell level correlation result in HTLV1+ samples
TIGIT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).