HIV Target gene Detail Information

> TICRR Gene Search Result

Gene Information

Gene Name	TICRR
Gene ID	90381
Gene Full Name	TOPBP1 interacting checkpoint and replication regulator
Gene Alias	SLD3; Treslin; C15orf42
Transcripts	ENSG00000140534
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q7Z2Z1
HGNC ID	HGNC:28704
VEGA ID	OTTHUMG00000149648
OMIM ID	613298
String ID	9606.ENSP00000268138
PharmGKB ID	PA142672278

Target gene [TICRR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007319	chr15	5	15		20	View
4012030	chr15	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TICRR expression and immune infiltrating cell level correlation result in HIV+ samples
TICRR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).