HIV Target gene Detail Information

> TIAM2 Gene Search Result

Gene Information

Gene Name	TIAM2
Gene ID	26230
Gene Full Name	T cell lymphoma invasion and metastasis 2
Gene Alias	STEF; TIAM-2
Transcripts	ENSG00000146426
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IVF5
HGNC ID	HGNC:11806
VEGA ID	OTTHUMG00000015880
OMIM ID	604709
String ID	9606.ENSP00000437188
PharmGKB ID	PA36515

Target gene [TIAM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003729	chr6	23	22	11	56	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TIAM2 expression and immune infiltrating cell level correlation result in HIV+ samples
TIAM2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TIAM2 expression and immune infiltrating cell level correlation result in HIV+ samples
TIAM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).