HIV Target gene Detail Information

> TIAL1 Gene Search Result

Gene Information

Gene Name	TIAL1
Gene ID	7073
Gene Full Name	TIA1 cytotoxic granule associated RNA binding protein like 1
Gene Alias	TCBP; TIAR
Transcripts	ENSG00000151923
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q01085
HGNC ID	HGNC:11804
VEGA ID	OTTHUMG00000019156
OMIM ID	603413
String ID	9606.ENSP00000358089
PharmGKB ID	PA36513

Target gene [TIAL1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003722	chr10	54	2		56	View
4006180	chr10	21	4	1	26	View
4008389	chr10	13	2		15	View
4008390	chr10	13	2		15	View
4011351	chr10	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TIAL1 expression and immune infiltrating cell level correlation result in HIV+ samples
TIAL1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TIAL1 expression and immune infiltrating cell level correlation result in HIV+ samples
TIAL1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).