HIV Target gene Detail Information

> TIA1 Gene Search Result

Gene Information

Gene Name	TIA1
Gene ID	7072
Gene Full Name	TIA1 cytotoxic granule associated RNA binding protein
Gene Alias	WDM; TIA-1
Transcripts	ENSG00000116001
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	P31483
HGNC ID	HGNC:11802
VEGA ID	OTTHUMG00000129644
OMIM ID	603518
String ID	9606.ENSP00000401371
PharmGKB ID	PA36511

Target gene [TIA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001434	chr2	73	89	4	166	View
4010125	chr2	8	2		10	View
4011996	chr2	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TIA1 expression and immune infiltrating cell level correlation result in HIV+ samples
TIA1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TIA1 expression and immune infiltrating cell level correlation result in HIV+ samples
TIA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).