HBV Target gene Detail Information

> THSD7B Gene Search Result


Gene Information
Gene Name THSD7B
Gene ID 80731
Gene Full Name thrombospondin type 1 domain containing 7B
Transcripts ENSG00000144229
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q9C0I4
HGNC ID HGNC:29348
VEGA ID OTTHUMG00000153590
String ID 9606.ENSP00000272643
PharmGKB ID PA162405776
Target gene [THSD7B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003099 chr2 12 52 102 166 View
1017135 chr2 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of THSD7B expression and immune infiltrating cell level correlation result in HBV+ samples
THSD7B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).