HBV Target gene Detail Information

> THEMIS Gene Search Result


Gene Information
Gene Name THEMIS
Gene ID 387357
Gene Full Name thymocyte selection associated
Gene Alias GASP; SPOT; TSEPA; C6orf190; C6orf207
Transcripts ENSG00000275122
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N1K5
HGNC ID HGNC:21569
VEGA ID OTTHUMG00000190250
OMIM ID 613607
String ID 9606.ENSP00000357231
PharmGKB ID PA165618330
Target gene [THEMIS] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1018539 chr6 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of THEMIS expression and immune infiltrating cell level correlation result in HBV+ samples
THEMIS expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).