Gene Information
Gene Name
|
THBS1 |
Gene ID
|
7057
|
Gene Full Name
|
thrombospondin 1 |
Gene Alias
|
TSP; THBS; TSP1; TSP-1; THBS-1 |
Transcripts
|
ENSG00000137801
|
Virus
|
HPV |
Gene Type
|
protein coding |
HPA Location Info
|
Plasma membrane;Predicted to be secreted;
|
HPA Protein Class Info
|
Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins |
Gene Function
|
Suppressor gene
|
Uniport_ID
|
P07996
|
HGNC ID
|
HGNC:11785
|
VEGA ID
|
OTTHUMG00000133665
|
OMIM ID
|
188060 |
String ID
|
9606.ENSP00000260356
|
PharmGKB ID
|
PA36497
|
Target gene [THBS1] related to VISs
DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
5400747 |
chr15 |
2 |
6 |
|
8 |
View |
Relationship between gene expression and immune infiltrating cell level
Data ID |
Disease |
Sample number |
Sample type |
GSE40774 (GEO) |
Head and neck squamous cell carcinoma |
134 |
Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1) |
GSE138080 (GEO) |
Cervical intraepithelial neoplasia |
25 |
Normal (10), Cervical intraepithelial neoplasia (HPV+)(15) |
HNSC (TCGA) |
Head and Neck squamous cell carcinoma |
566 |
Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44) |
> Dataset: GSE40774
|
HeatMap of cell type fractions in all samples
|
Lollipop of THBS1 expression and immune infiltrating cell level correlation result in HPV+ samples
|
THBS1 expression: Low -> High
|
|
|
> Dataset: GSE138080
|
HeatMap of cell type fractions in all samples
|
Lollipop of THBS1 expression and immune infiltrating cell level correlation result in HPV+ samples
|
THBS1 expression: Low -> High
|
|
|
> Dataset: HNSC
|
HeatMap of cell type fractions in all samples
|
Lollipop of THBS1 expression and immune infiltrating cell level correlation result in HPV+ samples
|
THBS1 expression: Low -> High
|
|
|
|
|