HIV Target gene Detail Information

> THAP4 Gene Search Result

Gene Information

Gene Name	THAP4
Gene ID	51078
Gene Full Name	THAP domain containing 4
Gene Alias	PP238; CGI-36
Transcripts	ENSG00000176946
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transcription factors
Uniport_ID	Q8WY91
HGNC ID	HGNC:23187
VEGA ID	OTTHUMG00000133410
OMIM ID	612533
String ID	9606.ENSP00000385006
PharmGKB ID	PA134864723

Target gene [THAP4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008491	chr2	14	1		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of THAP4 expression and immune infiltrating cell level correlation result in HIV+ samples
THAP4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).