HBV Target gene Detail Information

> TGM3 Gene Search Result

Gene Information

Gene Name	TGM3
Gene ID	7053
Gene Full Name	transglutaminase 3
Gene Alias	TGE; UHS2
Transcripts	ENSG00000125780
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Gene Function	Suppressor gene & Oncogene
Uniport_ID	Q08188
HGNC ID	HGNC:11779
VEGA ID	OTTHUMG00000031690
OMIM ID	600238
String ID	9606.ENSP00000370867
Drugbank ID	BE0001273
PharmGKB ID	PA36492

Target gene [TGM3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013051	chr20	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TGM3 expression and immune infiltrating cell level correlation result in HBV+ samples
TGM3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).