HIV Target gene Detail Information

> TGIF2 Gene Search Result


Gene Information
Gene Name TGIF2
Gene ID 60436
Gene Full Name TGFB induced factor homeobox 2
Transcripts ENSG00000118707
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Centrosome;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q9GZN2
HGNC ID HGNC:15764
VEGA ID OTTHUMG00000172332
OMIM ID 607294
String ID 9606.ENSP00000362981
PharmGKB ID PA38035
Target gene [TGIF2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4007918 chr20 15 2 17 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TGIF2 expression and immune infiltrating cell level correlation result in HIV+ samples
TGIF2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TGIF2 expression and immune infiltrating cell level correlation result in HIV+ samples
TGIF2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).