HBV Target gene Detail Information

> TGFBRAP1 Gene Search Result

Gene Information

Gene Name	TGFBRAP1
Gene ID	9392
Gene Full Name	transforming growth factor beta receptor associated protein 1
Gene Alias	VPS3; TRAP1; TRAP-1
Transcripts	ENSG00000135966
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WUH2
HGNC ID	HGNC:16836
VEGA ID	OTTHUMG00000130809
OMIM ID	606237
String ID	9606.ENSP00000377027
PharmGKB ID	PA134963946

Target gene [TGFBRAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003510	chr2	90	32	5	127	View
1011590	chr2	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TGFBRAP1 expression and immune infiltrating cell level correlation result in HBV+ samples
TGFBRAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).