HBV Target gene Detail Information

> TGFBI Gene Search Result


Gene Information
Gene Name TGFBI
Gene ID 7045
Gene Full Name transforming growth factor beta induced
Gene Alias CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
Transcripts ENSG00000120708
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Gene Function Suppressor gene
Uniport_ID Q15582
HGNC ID HGNC:11771
VEGA ID OTTHUMG00000163213
OMIM ID 601692
String ID 9606.ENSP00000416330
PharmGKB ID PA36484
Target gene [TGFBI] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007595 chr5 25 1 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TGFBI expression and immune infiltrating cell level correlation result in HBV+ samples
TGFBI expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).