HBV Target gene Detail Information

> TGFA Gene Search Result

Gene Information

Gene Name	TGFA
Gene ID	7039
Gene Full Name	transforming growth factor alpha
Gene Alias	TFGA
Transcripts	ENSG00000163235
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Predicted to be secreted;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins
Uniport_ID	P01135
HGNC ID	HGNC:11765
VEGA ID	OTTHUMG00000129669
OMIM ID	190170
String ID	9606.ENSP00000295400
PharmGKB ID	PA36480

Target gene [TGFA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016155	chr2		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TGFA expression and immune infiltrating cell level correlation result in HBV+ samples
TGFA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).