HIV Target gene Detail Information

> TGDS Gene Search Result

Gene Information

Gene Name	TGDS
Gene ID	23483
Gene Full Name	TDP-glucose 4,6-dehydratase
Gene Alias	TDPGD; SDR2E1; CATMANS
Transcripts	ENSG00000088451
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Nucleoli;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	O95455
HGNC ID	HGNC:20324
VEGA ID	OTTHUMG00000046308
OMIM ID	616146
String ID	9606.ENSP00000261296
PharmGKB ID	PA128395791

Target gene [TGDS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008926	chr13	13			13	View
4008927	chr13	13			13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TGDS expression and immune infiltrating cell level correlation result in HIV+ samples
TGDS expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TGDS expression and immune infiltrating cell level correlation result in HIV+ samples
TGDS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).