HBV Target gene Detail Information

> TFPI Gene Search Result

Gene Information

Gene Name	TFPI
Gene ID	7035
Gene Full Name	tissue factor pathway inhibitor
Gene Alias	EPI; TFI; LACI; TFPI1
Transcripts	ENSG00000003436
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Uniport_ID	P10646
HGNC ID	HGNC:11760
VEGA ID	OTTHUMG00000132634
OMIM ID	152310
String ID	9606.ENSP00000233156
Drugbank ID	BE0000967
PharmGKB ID	PA36475

Target gene [TFPI] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1014944	chr2		3		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TFPI expression and immune infiltrating cell level correlation result in HBV+ samples
TFPI expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).