Home
Virus
Gene
Disease
Dataset
Download
Help
 
HPV Target gene Detail Information

> TFAP2B Gene Search Result


Gene Information
Gene Name TFAP2B
Gene ID 7021
Gene Full Name transcription factor AP-2 beta
Gene Alias PDA2; AP-2B; AP2-B
Transcripts ENSG00000008196
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q92481
HGNC ID HGNC:11743
VEGA ID OTTHUMG00000014836
OMIM ID 601601
String ID 9606.ENSP00000377265
PharmGKB ID PA36460
Target gene [TFAP2B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5200062 chr6 3 3 View
5403700 chr6 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of TFAP2B expression and immune infiltrating cell level correlation result in HPV+ samples
TFAP2B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).