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HBV Target gene Detail Information

> TERT Gene Search Result


Gene Information
Gene Name TERT
Gene ID 7015
Gene Full Name telomerase reverse transcriptase
Gene Alias TP2; TRT; CMM9; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1
Transcripts ENSG00000164362
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Nuclear speckles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID O14746
HGNC ID HGNC:11730
VEGA ID OTTHUMG00000090357
OMIM ID 187270
String ID 9606.ENSP00000309572
Drugbank ID BE0002449
PharmGKB ID PA36447
Target gene [TERT] related to virus gene/protein/region
IDPMIDMutationGene/Protein/RegionDescriptionDetail
1 22962577 C1653T
C Promoter
G
C
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Showing 1 to 1 of 1 entries
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Target gene [TERT] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
1000496 chr5 1283 472 318 2073 View
1000499 chr5 1282 472 317 2071 View
1000500 chr5 1282 472 317 2071 View
1000508 chr5 1286 469 299 2054 View
1000509 chr5 1260 468 326 2054 View
1000510 chr5 1262 467 316 2045 View
1000511 chr5 1271 467 303 2041 View
1000520 chr5 1284 469 264 2017 View
1000524 chr5 1224 465 317 2006 View
1000526 chr5 1210 463 326 1999 View
Showing 1 to 10 of 638 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TERT expression and immune infiltrating cell level correlation result in HBV+ samples
TERT expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).