HPV Target gene Detail Information

> TEKT5 Gene Search Result

Gene Information

Gene Name	TEKT5
Gene ID	146279
Gene Full Name	tektin 5
Gene Alias	CT149
Transcripts	ENSG00000153060
Virus	HPV
Gene Type	protein coding
HPA Location Info	Actin filaments;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96M29
HGNC ID	HGNC:26554
VEGA ID	OTTHUMG00000129750
OMIM ID	618686
String ID	9606.ENSP00000283025
PharmGKB ID	PA162405603

Target gene [TEKT5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5000568	chr16	115	16	2	133	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO)	Oropharyngeal squamous cell carcinoma	16	Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO)	Oropharyngeal squamous cell carcinoma	23	Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

> Dataset: GSE55546
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

> Dataset: GSE55544
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of TEKT5 expression and immune infiltrating cell level correlation result in HPV+ samples
TEKT5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: GSE140662