HIV Target gene Detail Information

> TDRD3 Gene Search Result

Gene Information

Gene Name	TDRD3
Gene ID	81550
Gene Full Name	tudor domain containing 3
Transcripts	ENSG00000083544
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H7E2
HGNC ID	HGNC:20612
VEGA ID	OTTHUMG00000017007
OMIM ID	614392
String ID	9606.ENSP00000440190
PharmGKB ID	PA134962690

Target gene [TDRD3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005163	chr13	35			35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TDRD3 expression and immune infiltrating cell level correlation result in HIV+ samples
TDRD3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TDRD3 expression and immune infiltrating cell level correlation result in HIV+ samples
TDRD3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).