HIV Target gene Detail Information

> TDP2 Gene Search Result

Gene Information

Gene Name	TDP2
Gene ID	51567
Gene Full Name	tyrosyl-DNA phosphodiesterase 2
Gene Alias	EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3
Transcripts	ENSG00000111802
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O95551
HGNC ID	HGNC:17768
VEGA ID	OTTHUMG00000014360
OMIM ID	605764
String ID	9606.ENSP00000367440
PharmGKB ID	PA165618310

Target gene [TDP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001836	chr6	124	4		128	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TDP2 expression and immune infiltrating cell level correlation result in HIV+ samples
TDP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).