HIV Target gene Detail Information

> TDG Gene Search Result

Gene Information

Gene Name	TDG
Gene ID	6996
Gene Full Name	thymine DNA glycosylase
Gene Alias	hTDG
Transcripts	ENSG00000139372
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q13569
HGNC ID	HGNC:11700
VEGA ID	OTTHUMG00000168418
OMIM ID	601423
String ID	9606.ENSP00000376611
PharmGKB ID	PA36419

Target gene [TDG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007493	chr12	12	7		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TDG expression and immune infiltrating cell level correlation result in HIV+ samples
TDG expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TDG expression and immune infiltrating cell level correlation result in HIV+ samples
TDG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).