HBV Target gene Detail Information

> TCF7L1 Gene Search Result

Gene Information

Gene Name	TCF7L1
Gene ID	83439
Gene Full Name	transcription factor 7 like 1
Gene Alias	TCF3; TCF-3
Transcripts	ENSG00000152284
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9HCS4
HGNC ID	HGNC:11640
VEGA ID	OTTHUMG00000130026
OMIM ID	604652
String ID	9606.ENSP00000282111
PharmGKB ID	PA36393

Target gene [TCF7L1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008493	chr2	15	5		20	View
1402248	chr2	15	5		20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TCF7L1 expression and immune infiltrating cell level correlation result in HBV+ samples
TCF7L1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).