HBV Target gene Detail Information

> TCF12 Gene Search Result

Gene Information

Gene Name	TCF12
Gene ID	6938
Gene Full Name	transcription factor 12
Gene Alias	HEB; p64; CRS3; HTF4; TCF-12; bHLHb20; HsT17266
Transcripts	ENSG00000140262
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q99081
HGNC ID	HGNC:11623
VEGA ID	OTTHUMG00000132047
OMIM ID	600480
String ID	9606.ENSP00000388940
PharmGKB ID	PA36381

Target gene [TCF12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003704	chr15	105		10	115	View
1003847	chr15	96		9	105	View
1008204	chr15	19	3		22	View
1014211	chr15	4			4	View
1400186	chr15	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TCF12 expression and immune infiltrating cell level correlation result in HBV+ samples
TCF12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).