HBV Target gene Detail Information

> TBXAS1 Gene Search Result

Gene Information

Gene Name	TBXAS1
Gene ID	6916
Gene Full Name	thromboxane A synthase 1
Gene Alias	TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14
Transcripts	ENSG00000059377
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P24557
HGNC ID	HGNC:11609
VEGA ID	OTTHUMG00000157302
OMIM ID	274180
String ID	9606.ENSP00000389414
Drugbank ID	BE0001893
PharmGKB ID	PA349

Target gene [TBXAS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010938	chr7	1	6	3	10	View
1401594	chr7	1	6	3	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TBXAS1 expression and immune infiltrating cell level correlation result in HBV+ samples
TBXAS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).