HIV Target gene Detail Information

> TBX6 Gene Search Result

Gene Information

Gene Name	TBX6
Gene ID	6911
Gene Full Name	T-box 6
Gene Alias	SCDO5
Transcripts	ENSG00000149922
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	O95947
HGNC ID	HGNC:11605
VEGA ID	OTTHUMG00000132115
OMIM ID	602427
String ID	9606.ENSP00000378650
PharmGKB ID	PA36368

Target gene [TBX6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006348	chr16	17	8		25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TBX6 expression and immune infiltrating cell level correlation result in HIV+ samples
TBX6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).