HIV Target gene Detail Information

> TBPL1 Gene Search Result


Gene Information
Gene Name TBPL1
Gene ID 9519
Gene Full Name TATA-box binding protein like 1
Gene Alias TLF; TLP; STUD; TRF2; MGC:8389; MGC:9620
Transcripts ENSG00000028839
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Nucleoli;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID P62380
HGNC ID HGNC:11589
VEGA ID OTTHUMG00000015609
OMIM ID 605521
String ID 9606.ENSP00000237264
PharmGKB ID PA36353
Target gene [TBPL1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004499 chr6 16 23 4 43 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TBPL1 expression and immune infiltrating cell level correlation result in HIV+ samples
TBPL1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TBPL1 expression and immune infiltrating cell level correlation result in HIV+ samples
TBPL1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).