HIV Target gene Detail Information

> TBP Gene Search Result

Gene Information

Gene Name	TBP
Gene ID	6908
Gene Full Name	TATA-box binding protein
Gene Alias	HDL4; GTF2D; SCA17; TFIID; GTF2D1
Transcripts	ENSG00000112592
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	P20226
HGNC ID	HGNC:11588
VEGA ID	OTTHUMG00000016084
OMIM ID	600075
String ID	9606.ENSP00000375942
PharmGKB ID	PA36352

Target gene [TBP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003547	chr8	43	16		59	View
4006130	chr8	24	3		27	View
4011523	chr8	4	2		6	View
4013221	chr6	4			4	View
4016429	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TBP expression and immune infiltrating cell level correlation result in HIV+ samples
TBP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TBP expression and immune infiltrating cell level correlation result in HIV+ samples
TBP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).