HIV Target gene Detail Information

> TBL1XR1 Gene Search Result


Gene Information
Gene Name TBL1XR1
Gene ID 79718
Gene Full Name transducin beta like 1 X-linked receptor 1
Gene Alias C21; DC42; IRA1; MRD41; TBLR1
Transcripts ENSG00000177565
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9BZK7
HGNC ID HGNC:29529
VEGA ID OTTHUMG00000157140
OMIM ID 608628
String ID 9606.ENSP00000405574
PharmGKB ID PA134928556
Target gene [TBL1XR1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4016336 chr3 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TBL1XR1 expression and immune infiltrating cell level correlation result in HIV+ samples
TBL1XR1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TBL1XR1 expression and immune infiltrating cell level correlation result in HIV+ samples
TBL1XR1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).