HTLV1 Target gene Detail Information

> TBCB Gene Search Result

Gene Information

Gene Name	TBCB
Gene ID	1155
Gene Full Name	tubulin folding cofactor B
Gene Alias	CG22; CKAP1; CKAPI
Transcripts	ENSG00000105254
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q99426
HGNC ID	HGNC:1989
VEGA ID	OTTHUMG00000048143
OMIM ID	601303
String ID	9606.ENSP00000221855
PharmGKB ID	PA162405357

Target gene [TBCB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009631	chr19	23	13		36	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TBCB expression and immune infiltrating cell level correlation result in HTLV1+ samples
TBCB expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of TBCB expression and immune infiltrating cell level correlation result in HTLV1+ samples
TBCB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).