HTLV1 Target gene Detail Information

> TBC1D9B Gene Search Result

Gene Information

Gene Name	TBC1D9B
Gene ID	23061
Gene Full Name	TBC1 domain family member 9B
Gene Alias	GRAMD9B
Transcripts	ENSG00000284400
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q66K14
HGNC ID	HGNC:29097
VEGA ID	OTTHUMG00000130911
OMIM ID	618039
String ID	9606.ENSP00000349291
PharmGKB ID	PA145148062

Target gene [TBC1D9B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001968	chr5	58	224	25	307	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TBC1D9B expression and immune infiltrating cell level correlation result in HTLV1+ samples
TBC1D9B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of TBC1D9B expression and immune infiltrating cell level correlation result in HTLV1+ samples
TBC1D9B expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of TBC1D9B expression and immune infiltrating cell level correlation result in HTLV1+ samples
TBC1D9B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).